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Search Results for " tyrosine-protein kinase btk "

Targets

4

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4337 PCI 29732 PCI29732,PCI-29732 Others , BCRP , BTK
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
T1835 Ibrutinib PCI-32765 Tyrosine Kinases , Src , BTK , Ligands for Target Protein for PROTAC
Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.
T6217 LFM-A13 PLK , JAK , BTK
LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.
T75133 NRX-0492
NRX-0492 is an orally administered compound that efficiently degrades Bruton's tyrosine kinase (BTK) by catalyzing its ubiquitylation and subsequent proteasomal degradation, achieving half-maximal degradation concentrati...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-02271 BTK Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activatio...
TargetMol